I had a really interesting question in clinic this week about how gut health affects other areas of the body. It’s a great question – because your gut is connected to almost every other system you have. One of the most common issues I hear about is constant fatigue – that ongoing feeling of tiredness that just won’t shift.
When you’re dealing with constant fatigue, it affects everything — work, family life, study, motivation and mood. If you feel like you’re running on empty all the time, it’s absolutely worth exploring why. Let’s look at how your gut could be playing a major role.
1. Impaired absorption – the link between gut health and constant fatigue
If your digestive system isn’t working at its best, it may not be breaking down and absorbing nutrients properly. That means key vitamins and minerals are simply passing straight through without being used.
Low stomach acid or poor enzyme production from the pancreas can reduce nutrient absorption — and this lack of nutrients may be a major reason for constant fatigue.
2. Your microbiome might be behind your constant fatigue
Further along the digestive tract, your microbiome (your gut bacteria) have a huge influence on digestion, hormone balance, mood and even sleep. All of these contribute to healthy energy levels.
Stress – whether emotional, environmental or from an infection – can disrupt your microbiome. When bacterial balance is thrown off, less desirable species or yeasts like candida may take over. This can affect both digestion and energy — leading to constant fatigue.
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Research has shown that people experiencing persistent tiredness often have lower bacterial diversity too. This is one reason I’m cautious about overly-restrictive diets for gut issues — a diverse diet helps build a diverse microbiome, which supports better energy.
3. Inflammation
When more pathogenic (unhelpful) bacteria are present, they can trigger inflammation in the gut as your immune system tries to fight them off. Think about when you get a cold — you often feel wiped out for a few days. Chronic gut inflammation is subtler but can go on for months or even years, contributing to ongoing constant fatigue in the background.
4. Gut lining (mucosal integrity)
Your gut lining’s job is to keep unwanted particles out and allow nutrients in. When this lining becomes compromised, it can lead to what’s often called ‘leaky gut’. As particles pass through the gut wall, your immune system launches a response — this inflammation can create feelings of exhaustion and constant fatigue over time. Ongoing inflammation can gradually weaken the gut wall further, continuing the cycle.
5. The HPA Axis – a big player in constant fatigue
The HPA axis (hypothalamic-pituitary-adrenal axis) is your body’s stress-response system. When inflammation increases, the body releases more stress hormones such as cortisol. If this continues for too long, it can lead to adrenal dysregulation, insomnia and exhaustion — all of which can cause constant fatigue.
What to do next
If you’re struggling with constant fatigue, it’s important to start with your GP to rule out anything urgent. But if those tests come back clear — and especially if you have accompanying gut symptoms — gut testing may provide the answers you’ve been looking for.
You don’t have to keep running on empty.
If you’re ready to explore what’s really going on, I’d love to chat.
👉 Book a FREE 30-minute call using the link below – so we can talk through your symptoms and see what the next steps might look like.
If you would like to speak to me about any aspect of your gut health, then please use this link to book into my diary for a FREE 30 minute chat so I can find out more about what is going on for you. Alternatively please use the ‘Learn More’ link below.
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